by The anthelmintic fenbendazole, which is used to treat parasitic infections in animals, has shown anticancer effects in human cancer cells. The drug reduces glucose uptake in cancer cells and interferes with cell signaling pathways.
The anecdotal evidence isn’t reliable. Tippens was also taking conventional cancer treatments at the time of his remission, which could have contributed to his improvement.
Dosage
Fenbendazole is an antiparasitic drug with a broad range of activity in animals. It works by binding to b-tubulin microtubule subunits and disrupting their polymerization. It is currently used as an anthelmintic for livestock and dogs, but preclinical studies suggest it could also be useful as a cancer treatment. The Joe Tippens Protocol, a treatment method popularized by a video on TikTok and Facebook, recommends taking 222 mg of the medication seven days a week. The medication is available in granules and capsules and can be taken with food.
Earlier this year, a cancer patient named Joe Tippens claimed that fenbendazole (also known as Febantel) cured his advanced lung cancer. He had reported that he was cured after receiving immunotherapy treatments in a clinical trial and taking fenbendazole. Although his story is compelling, it should be viewed with caution. The information he provided about his experience was disseminated through social media, and it may be untrue.
Researchers have found that fenbendazole can be an effective anticancer agent because it targets multiple cellular pathways. This is an advantage over drugs that target only one pathway, which often fail to provide a significant benefit and can lead to resistance. In addition, fenbendazole interferes with glucose metabolism, which causes cancer cells to die. It has also been shown to inhibit the growth of tumors in mice.
Side effects
Fenbendazole is a drug that is used to treat parasitic infections in animals. It is also believed to be effective against some types of cancer. However, a video that has been circulated on TikTok and Facebook claims that this drug cures advanced lung cancer. This claim is unfounded and is based on anecdotal evidence. While there is some evidence that fenbendazole can slow cancer cell growth in cell cultures and mice, there isn’t sufficient evidence to prove that it can cure cancer.
This drug interferes with the process that allows cancer cells to take up glucose for energy. This leads to a reduction in tumor size and survival. In addition, it has been shown to inhibit the formation of new tumors in mice with large B-cell lymphoma that had metastasized. Moreover, fenbendazole was found to be safe for humans and is known to have a high safety margin.
Nonetheless, it is important to discuss any supplements you are taking with your healthcare provider. Some supplements can interact with fenbendazole and reduce its effectiveness or cause side effects. In addition, some may interfere with your ability to absorb the drug. The Joe Tippens protocol recommends a dose of 222 mg per day, taken seven days a week. The medication is available in oral granules and liquid suspension and should be taken with food.
Safety
Fenbendazole is a broad-spectrum benzimidazole anthelminthic (methyl N-(6-phenylsulfanyl-1H-benzimidazol-2-yl) carbamate) that has been used for decades to treat parasites and worms in animal species. It is the main drug in the Joe Tippens Cancer Protocol, and it was recently found to stall glioblastoma tumor growth. Researchers found that fenbendazole interferes with cancer cells’ ability to take up glucose for energy, which can cause them to starve. This may be the key to the Joe Tippens Protocol’s effectiveness.
The study also found that fenbendazole works as an anti-proliferative agent by destroying cell structures such as mitochondria and the cell membrane. In addition, fenbendazole disrupts microtubules and stabilizes p53, two important genes involved in cell cycle regulation. This multi-targeted effect is likely to improve efficacy and circumvent the development of resistance that can occur with single-target drugs.
However, Health Feedback has determined that there is no evidence to support Tippens’ claim that fenbendazole can cure cancer. The anthelmintic has not undergone clinical trials to prove its safety and effectiveness as a cancer treatment. Moreover, the Food and Drug Administration has not approved fenbendazole for treating cancer in humans. Nonetheless, the findings of this research may inspire further investigation into the potential use of benzimidazole medications in humans with cancer.
Availability
The drug fenbendazole is an anti-parasitic medication used in livestock. It has been shown to have anti-tumor activity in mice and humans. However, it is not approved for use in humans. Sheila Singh, a cancer specialist at McMaster University in Ontario, debunked the videos of a veterinarian who claimed that he had cured cancer by taking fenbendazole. Singh said the video’s claim was false, but that anthelmintics, such as fenbendazole, merited further research.
In a cell culture study, fenbendazole caused significant decreases in the number of EMT6 cells after 2-h treatment. The effect was dose-dependent and occurred at drug concentrations near the limit of solubility. Severe hypoxia increased the toxicity of fenbendazole in EMT6 cells. Cell viability was also assessed by clonogenicity, which was reduced in the presence of the drug.
Another study of fenbendazole in BALB/c mice was conducted to determine the effects of a dietary supplement containing the drug on the growth of tumors. Tumors were measured every week until they reached a volume of 1000 mm3. The mice were then stratified by tumor volume and given three daily injections of fenbendazole or a placebo. Neither the diet nor the injections affected tumor growth in unirradiated or irradiated mice. The data support the hypothesis that fenbendazole inhibits growth and radiation response of human cancer cells by interfering with microtubule polymerization and glucose uptake. fenbendazole for humans cancer
